Handbook of Biological Dyes and Stains: Synthesis and Industrial Applications PDF by R. W. Sabnis

Contents

Preface
Color has been a fascination for individuals for a long time. The book is intended as a reference guide for dyes used in biology, chemistry, histology, cytology, medicine, microscopy, and all color- and medical-related allied fields.

Even though the use of biological dyes is widespread, it is growing rapidly, and has exploded in the last decade, there is no book available in the market directly on these dyes that provides information, such as CAS registry numbers, safety/toxicity data, and various applications, in one source. Hence, there was a need to publish a book that provided an immediate incentive for compiling the notes to update the scientific community with the wealth of information on biological dyes and stains. The dyestuff literature, particularly on biological dyes and stains, is largely in patents. This book, as a reference handbook, provides systematic and up-to-date library of information on 200þ biological dyes and stains. The book is compiled as a resource guide for biologists, chemists, histologists, cytologists, medical professionals, and nonchemists in industry as well as in university.

Biological dyes and stains are arranged alphabetically by the most commonly used name. Again, the choice of primary name is somewhat arbitrary, but an effort has been made to strike a balance between names that are easily recognizable and names that are chemically informative.

The detailed information on each biological dye or stain is covered in the following order: CAS registry number, chemical structure, CA index name, other names, Merck index number (Merck Index 14th Edition, 2006), chemical/ dye class, molecular formula, molecular weight, physical form, solubility, melting point, boiling point, pH range, color change at pH, pKa, absorption (lmax), emission (lmax), synthesis, staining applications, biological applications, industrial applications, safety/toxicity, certification/ approval, and references. Where there are discrepancies between different values, the author has used his judgment on selecting the most likely value.

Numerous recent references have been provided on various synthetic methods, staining applications, biological applications, industrial applications, and safety/toxicity data. Space and format limitations prevent giving all the references for each dye. This is the first ever book that provides safety/toxicity data with reference to acute toxicity, aquatic toxicity, carcinogenicity, cytotoxicity, chronic toxicity, ecotoxicity, genotoxicity, hematotoxicity, hepatotoxicity, immunotoxicity, microbial toxicity, mutagenicity, nephrotoxicity, neurotoxicity, nucleic acid damage, oral toxicity, phototoxicity, phytotoxicity, skin toxicity, reproductive toxicity, and so on. The book also provides Biological Stain Commission (BSC)-certified dyes and Food & Drug Administration (FDA)-approved dyes.

Several appendixes have been provided at the end of the book for scientists to conveniently and easily find a dye as per their need. These appendixes include CAS registry numbers, BSC-certified dyes, FDA-approved dyes, metal indicators, nucleic acid stains, organelle probes, and pH indicators.

Omissions as well as errors of fact and interpretation are inevitable in dealing with so vast a subject as biological dyes. I shall be glad to have my attention drawn to errors and to incorporate suggestions for improvement when a revision becomes possible.

I express my profound respect and appreciation to my guru/mentor/advisor, Prof. D.W. Rangnekar, who brought me to this wonderful world of color science in the Dyestuff Technology Department of Mumbai University Institute of Chemical Technology (MUICT), where I laid the foundation stone for my research career in dye chemistry. It is my pleasure to make grateful acknowledgement to Dr. Alan Fanta, Dr. Ganapati Shankarling, and Dr. Jeffrey Talkington for their extremely useful discussions, encouragement, and inspiration.

Words are inadequate to express my sincere appreciation formywife Madhuri and daughter Anika. It would not have been possible to write this book without their encouragement and patience. It is a great pleasure to express my gratitude to JohnWiley & Sons, Inc. for giving me an opportunity to write this book.